2-IMINOBIOTIN HYDROBROMIDE
2-Iminobiotin hydrobromide
CAS: 76985-52-9
Molecular Formula: C10H18BrN3O2S
2-IMINOBIOTIN HYDROBROMIDE - Names and Identifiers
2-IMINOBIOTIN HYDROBROMIDE - Physico-chemical Properties
| Molecular Formula | C10H18BrN3O2S |
| Molar Mass | 324.23782 |
| Storage Condition | 2-8℃ |
| In vitro study | Application of low concentrations of 2-Iminobiotin (2-IB; 10 ng/mL and 30 ng/mL) superimposed on hypothermia abrogates the hypoxia-induced lactate dehydrogenase (LDH) increase, resulting in LDH levels that were not different from the normoxia control. |
2-IMINOBIOTIN HYDROBROMIDE - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.084 ml | 15.421 ml | 30.841 ml |
| 5 mM | 0.617 ml | 3.084 ml | 6.168 ml |
| 10 mM | 0.308 ml | 1.542 ml | 3.084 ml |
| 5 mM | 0.062 ml | 0.308 ml | 0.617 ml |
Last Update：2024-01-02 23:10:35
2-IMINOBIOTIN HYDROBROMIDE - Reference Information
| Biological activity | 2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible inhibitor of NO synthase, acting on mouse iNOS and rat n-cNOS with Ki values of 21.8 and 37.5 μM respectively. The 2-Iminobiotin hydrobromide and low temperature environment can protect human nerve cells from hypoxia-induced cell damage. |
| target | NO synthases |
Last Update：2024-04-10 22:29:15
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